EDH Optimizer
Infect Commander decks
Infect swaps 40 life for 10 poison counters, so it kills far faster than any normal damage plan. The trade-off is a giant target: the table knows two connections are enough.
Cards that define the archetype
Ranked by how much MORE they are played inside the archetype than in the rest of Commander. Generic staples (Sol Ring, Arcane Signet…) fall out for exactly that reason: they are played everywhere equally.
| Card | Commanders | Avg. inclusion | Excess |
|---|---|---|---|
| Karn's Bastion | 25 | 59% | +41 pts |
| Infectious Inquiry | 11 | 59% | +20 pts |
| Vraska's Fall | 11 | 56% | +20 pts |
| Contagion Clasp | 11 | 56% | +19 pts |
| White Sun's Twilight | 10 | 53% | +18 pts |
| Blightbelly Rat | 10 | 55% | +18 pts |
| Drown in Ichor | 10 | 51% | +18 pts |
| Evolution Sage | 11 | 61% | +16 pts |
| Bloated Contaminator | 9 | 50% | +16 pts |
| Thrummingbird | 9 | 67% | +15 pts |
| Infectious Bite | 8 | 49% | +14 pts |
| Venerated Rotpriest | 8 | 50% | +14 pts |
| Contagion Engine | 8 | 48% | +14 pts |
| Cankerbloom | 8 | 57% | +13 pts |
| Ichor Rats | 7 | 56% | +13 pts |
| Skrelv's Hive | 7 | 61% | +13 pts |
| Norn's Decree | 7 | 49% | +13 pts |
| Myr Convert | 7 | 40% | +12 pts |
| Vraska, Betrayal's Sting | 7 | 49% | +12 pts |
| Skrelv, Defector Mite | 7 | 56% | +12 pts |
| Unnatural Restoration | 7 | 61% | +12 pts |
| Everflowing Chalice | 8 | 56% | +12 pts |
| Contentious Plan | 7 | 57% | +12 pts |
| Experimental Augury | 7 | 61% | +12 pts |
| Inexorable Tide | 7 | 64% | +12 pts |
| Tezzeret's Gambit | 7 | 67% | +11 pts |
| Flux Channeler | 7 | 65% | +11 pts |
| Prologue to Phyresis | 6 | 58% | +11 pts |
| Plague Myr | 6 | 52% | +11 pts |
| Glistening Sphere | 6 | 53% | +11 pts |
Commanders for Infect
Ranked by how central this archetype is to their decks and by how played each commander is, according to EDHREC data.
By color identity
Black
Green
Black · Green
Blue
Blue · Green
Blue · Black
Paste your list and we tell you whether the deck actually does what it wants to do: curve, ramp, interaction and a 10,000-game simulation.
🛠️ Build a deck like this 📥 Analyze my deckFrequently asked questions
What is the best commander for a Infect deck?
The most-built commanders for this archetype are Atraxa, Praetors' Voice, Vishgraz, the Doomhive, Agent Frank Horrigan. EDH Optimizer has the full list of 158 commanders with their recommended cards, ranked by how central Infect is to their decks.
Which cards are must-haves in a Infect deck?
The three most characteristic are Karn's Bastion, Infectious Inquiry, Vraska's Fall. They are not the most-played cards in the format, but the ones that appear far more inside this archetype than in the rest of Commander — which is what actually makes them essential here.
What colors is Infect played in?
The most common color identities are Black, Green, Black · Green. The "By color identity" section groups the commanders and links to the best cards for each combination.
How much does a Infect deck cost?
It depends on the price cap PER CARD you set. Each commander page lists the best cards in three tiers (up to €2, up to €10 and no cap), and the optimizer only suggests swaps that fit the cap you pick.